MeSH Browser

MeSH Heading: Inactivation, Metabolic
Tree Number(s): G03.171.450; G03.787.225.450; G07.690.725.225.450
Unique ID: D008658
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008658
Annotation: restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /‌pharmacokin (IM) or /‌metab
Scope Note: Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes those metabolic transformations that make the substance more soluble for faster renal excretion.
Entry Term(s): Detoxication, Drug, Metabolic; Detoxification, Drug, Metabolic; Drug Detoxication, Metabolic; Metabolic Detoxication, Drug; Metabolic Detoxification, Drug; Metabolic Drug Inactivation
NLM Classification #: QV 38.5
Public MeSH Note: 2015; see METABOLIC DETOXICATION, DRUG 1980-2014; see BIOTRANSFORMATION 1970-1979
History Note: 2015 (1970); use BIOTRANSFORMATION 1970-1979
Date Established: 1980/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/06/30

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Inactivation, Metabolic MeSH Descriptor Data 2025