MeSH Browser

MeSH Heading: Metabolic Detoxication, Phase II
Tree Number(s): G03.171.450.750; G03.787.225.450.750; G07.690.725.225.450.750
Unique ID: D050217
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050217
Scope Note: The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Entry Version: METAB DETOX PHASE II
Entry Term(s): Metabolic Detoxication, Conjugative; Metabolic Detoxification, Phase II; Phase II Detoxification
See Also: Antioxidant Response Elements; Protein Processing, Post-Translational
Public MeSH Note: 2006
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/06/30

Allowable Qualifiers: ethnology (EH)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0473296
Scope Note: The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Terms: Metabolic Detoxication, Phase II Preferred Term
Term UI T611369
Date09/29/2004
LexicalTag NON
ThesaurusID NLM (2006); Metabolic Detoxication, Conjugative
Term UI T611371
Date09/29/2004
LexicalTag NON
ThesaurusID NLM (2006); Phase II Detoxification
Term UI T626002
Date12/27/2004
LexicalTag NON
ThesaurusID NLM (2006); Metabolic Detoxification, Phase II
Term UI T611370
Date09/29/2004
LexicalTag NON
ThesaurusID NLM (2006)

Metabolic Detoxication, Phase II MeSH Descriptor Data 2024