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Plicamycin MeSH Descriptor Data 2024


MeSH Heading
Plicamycin
Tree Number(s)
D02.455.426.559.847.562.050.650
D04.615.562.050.650
D09.408.051.059.650
Unique ID
D008926
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008926
Scope Note
A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.
Entry Term(s)
Aureolic Acid
Mithramycin
Mitramycin
Pharm Action
Antibiotics, Antineoplastic
Fluorescent Dyes
Protein Synthesis Inhibitors
Nucleic Acid Synthesis Inhibitors
Calcium-Regulating Hormones and Agents
Related Numbers
18378-89-7
CAS Type 1 Name
Mithramycin
NLM Classification #
QV 269
Previous Indexing
Antibiotics, Antineoplastic (1967-1970)
Public MeSH Note
93; was MITHRAMYCIN 1973-92
Online Note
use PLICAMYCIN to search MITHRAMYCIN 1971-92 (as Prov 1971-72)
History Note
93; was MITHRAMYCIN 1971-92 (Prov 1971-72)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2018/05/22
Plicamycin Preferred
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