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Pradimicins and Benanomicins MeSH Descriptor Data 2024


MeSH Heading
Pradimicins and Benanomicins
Tree Number(s)
D02.455.426.559.847.562.050.825
D02.540.576.750
D02.806.550.469
D04.345.674.750
D04.615.562.050.825
D09.408.051.059.825
Unique ID
D000095643
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000095643
Scope Note
Polycyclic aromatic polyketides with pentacyclic angular dihydrobenzo(a)naphthacenequinone skeletons. Pradimicin- and related benanomicin-type polyphenols are produced by Actinobacteria, e.g., ACTINOMADURA, using type II polyketide synthase involving condensation of one acetyl-CoA and nine malonyl-CoA. Pradimicins and benanomicins have an amino acid (e.g., D-ALANINE) and often a 5-O-sugar and bind to terminal D-mannosides of the cell wall of various fungi, e.g., CANDIDA. In addition to antifungal activity many pradimicins and benanomicins have anti-HIV activities.
Entry Term(s)
Benanomicin Antibiotics
Benanomicin and Pradimicin Antibiotics
Benanomicinones
Benanomicins
Benanomicins and Pradimicins
Pradimicin Antibiotics
Pradimicin and Benanomicin Antibiotics
Pradimicin-Like Polyketides
Pradimicin-Type Polyphenols
Pradimicinones
Pradimicins
Registry Number
0
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/14
Pradimicins and Benanomicins Preferred
Benanomicin Antibiotics Narrower
Pradimicin and Benanomicin Antibiotics Narrower
Benanomicinones Related
Pradimicin Antibiotics Narrower
Pradimicinones Related
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