MeSH Browser

MeSH Heading: Aclarubicin
Tree Number(s): D02.455.426.559.847.562.050.050; D04.615.562.050.050; D09.408.051.059.050
Unique ID: D015250
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015250
Scope Note: An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.
Entry Term(s): Aclacin; Aclacinomycin A; Aclaplastin; MA-144A1; NSC-208734
Pharm Action: Antibiotics, Antineoplastic
Topoisomerase II Inhibitors
Registry Numbers: 74KXF8I502; 0
Related Numbers: 57576-44-0
CAS Type 1 Name: 1-Naphthacenecarboxylic acid,(2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1alpha,2beta,4beta))-
Previous Indexing: Antibiotics, Antineoplastic (1967-1988); Naphthacenes (1966-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/05/16
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Aclarubicin MeSH Descriptor Data 2025