MeSH Browser

MeSH Heading: Mixed Connective Tissue Disease
Tree Number(s): C17.300.540
Unique ID: D008947
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008947
Annotation: a specific disease entity; do not confuse with CONNECTIVE TISSUE DISEASES
Scope Note: A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a speckled epidermal nuclear staining pattern on direct immunofluorescence.
Entry Version: MIXED CONNECTIVE TISSUE DIS
Entry Term(s): Connective Tissue Disease, Mixed; MCTD; Sharp Syndrome
NLM Classification #: QZ 192
Previous Indexing: Collagen Diseases (1972-1978); Lupus Erythematosus, Systemic (1972-1978); Scleroderma, Systemic (1972-1978)
Public MeSH Note: 79
History Note: 79
Date Established: 1979/01/01
Date of Entry: 1978/05/15
Revision Date: 2013/07/09

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0013961
Scope Note: A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a speckled epidermal nuclear staining pattern on direct immunofluorescence.
Terms: Mixed Connective Tissue Disease Preferred Term
Term UI T026755
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); MCTD
Term UI T026753
Date03/16/1981
LexicalTag ABB
ThesaurusID UNK (19XX); Connective Tissue Disease, Mixed
Term UI T026754
Date05/15/1978
LexicalTag NON
ThesaurusID UNK (19XX); Sharp Syndrome
Term UI T026756
Date05/15/1978
LexicalTag EPO
ThesaurusID UNK (19XX)

Mixed Connective Tissue Disease MeSH Descriptor Data 2024