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Dermatomyositis MeSH Descriptor Data 2022


MeSH Heading
Dermatomyositis
Tree Number(s)
C05.651.594.819.500
C10.668.491.562.575.500
C17.300.250
C17.800.185
Unique ID
D003882
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003882
Annotation
coordinate with PARANEOPLASTIC SYNDROMES if pertinent
Scope Note
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
Entry Term(s)
Dermatomyositis, Adult Type
Dermatomyositis, Childhood Type
Dermatopolymyositis
Juvenile Dermatomyositis
Juvenile Myositis
Polymyositis-Dermatomyositis
NLM Classification #
WE 550
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2018/10/10
Dermatomyositis Preferred
Dermatomyositis, Adult Type Narrower
Dermatomyositis, Childhood Type Narrower
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