- Concept UI
- M0006061
- Scope Note
- A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)
- Terms
-
Dermatomyositis
Preferred Term
Term UI
T011553
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1966)
-
Polymyositis-Dermatomyositis
Term UI
T372461
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)
-
Dermatopolymyositis
Term UI
T372462
Date11/03/1999
LexicalTag
NON
ThesaurusID
NLM (2000)