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Molindone MeSH Descriptor Data 2022


MeSH Heading
Molindone
Tree Number(s)
D03.633.100.473.629
Unique ID
D008972
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008972
Scope Note
An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)
Entry Term(s)
Moban
Molindone Hydrochloride
Molindone Monohydrochloride
Pharm Action
Antipsychotic Agents
Registry Number
RT3Y3QMF8N
Related Numbers
15622-65-8
1DWS68PNE6
7416-34-4
CAS Type 1 Name
4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-
Previous Indexing
Antidepressive Agents (1966-1971)
Indoles (1966-1971)
Public MeSH Note
91; was see under INDOLES 1972-90
History Note
91(72); was see under INDOLES 1972-90
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2017/05/24
Molindone Preferred
Moban Narrower
Molindone Hydrochloride Narrower
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