MeSH Browser

MeSH Heading: Vemurafenib
Tree Number(s): D02.065.884.919; D02.886.590.700.919; D03.633.100.473.936
Unique ID: D000077484
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077484
Scope Note: An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA.
Entry Term(s): PLX 4032; PLX4032; R05185426; RG-7204; RG7204; Zelboraf
Pharm Action: Antineoplastic Agents
Protein Kinase Inhibitors
CAS Type 1 Name: 1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-
Public MeSH Note: 2019; VEMURAFENIB was indexed under INDOLES and SULFONAMIDES 2010-2018
History Note: 2019 (2010)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Vemurafenib MeSH Descriptor Data 2024