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Vemurafenib
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Vemurafenib
Tree Number(s)
D02.065.884.919
D02.886.590.700.919
D03.633.100.473.936
Unique ID
D000077484
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077484
Scope Note
An indole sulfonamide compound and inhibitor of
BRAF KINASES
that is used for the treatment of unresectable or metastatic
MELANOMA
.
Entry Term(s)
PLX 4032
PLX4032
R05185426
RG-7204
RG7204
Zelboraf
Pharm Action
Antineoplastic Agents
Protein Kinase Inhibitors
CAS Type 1 Name
1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-
Public MeSH Note
2019; VEMURAFENIB was indexed under INDOLES and SULFONAMIDES 2010-2018
History Note
2019 (2010)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Organic Chemicals [D02]
Amides [D02.065]
Sulfonamides [D02.065.884]
Benzenesulfonamides [D02.065.884.060]
Benzolamide [D02.065.884.120]
Bumetanide [D02.065.884.150]
Clopamide [D02.065.884.390]
Darunavir [D02.065.884.438]
Dichlorphenamide [D02.065.884.485]
Ethoxzolamide [D02.065.884.500]
Indapamide [D02.065.884.540]
Mefruside [D02.065.884.575]
Metolazone [D02.065.884.600]
Probenecid [D02.065.884.625]
Rosuvastatin Calcium [D02.065.884.650]
Sildenafil Citrate [D02.065.884.675]
Sulfanilamides [D02.065.884.725]
Sulfasalazine [D02.065.884.730]
Sumatriptan [D02.065.884.750]
Tamsulosin [D02.065.884.863]
Torsemide [D02.065.884.891]
Vemurafenib [D02.065.884.919]
Xipamide [D02.065.884.975]
Zonisamide [D02.065.884.987]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Sulfones [D02.886.590]
Sulfonamides [D02.886.590.700]
Benzenesulfonamides [D02.886.590.700.090]
Benzolamide [D02.886.590.700.120]
Benzothiadiazines [D02.886.590.700.135]
Bosentan [D02.886.590.700.143]
Bumetanide [D02.886.590.700.150]
Celecoxib [D02.886.590.700.247]
Chlorthalidone [D02.886.590.700.365]
Clopamide [D02.886.590.700.390]
Darunavir [D02.886.590.700.400]
Dichlorphenamide [D02.886.590.700.410]
Ethoxzolamide [D02.886.590.700.420]
Indapamide [D02.886.590.700.540]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine [D02.886.590.700.545]
Mafenide [D02.886.590.700.570]
Mefruside [D02.886.590.700.575]
Metolazone [D02.886.590.700.600]
Probenecid [D02.886.590.700.625]
Rosuvastatin Calcium [D02.886.590.700.650]
Sildenafil Citrate [D02.886.590.700.675]
Simeprevir [D02.886.590.700.700]
Sulfanilamides [D02.886.590.700.725]
Sulfasalazine [D02.886.590.700.730]
Sumatriptan [D02.886.590.700.750]
Tamsulosin [D02.886.590.700.863]
Torsemide [D02.886.590.700.891]
Vemurafenib [D02.886.590.700.919]
Xipamide [D02.886.590.700.975]
Zonisamide [D02.886.590.700.987]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Adrenochrome [D03.633.100.473.025]
Alcian Blue [D03.633.100.473.050]
Carbazoles [D03.633.100.473.144]
Cytochalasins [D03.633.100.473.231]
Delavirdine [D03.633.100.473.250]
Duocarmycins [D03.633.100.473.278]
Fluvastatin [D03.633.100.473.305]
Gliotoxin [D03.633.100.473.360]
Hydroxytryptophol [D03.633.100.473.385]
Ibogaine [D03.633.100.473.390]
Indapamide [D03.633.100.473.391]
Indican [D03.633.100.473.393]
Indigo Carmine [D03.633.100.473.396]
Indocyanine Green [D03.633.100.473.400]
Indole Alkaloids [D03.633.100.473.402]
Indoleacetic Acids [D03.633.100.473.404]
Indolequinones [D03.633.100.473.412]
Indolosesquiterpenes [D03.633.100.473.416]
Indomethacin [D03.633.100.473.420]
Indoramin [D03.633.100.473.432]
Iprindole [D03.633.100.473.469]
Isatin [D03.633.100.473.525]
Methisazone [D03.633.100.473.615]
Molindone [D03.633.100.473.629]
Oxyphenisatin Acetate [D03.633.100.473.725]
Panobinostat [D03.633.100.473.746]
Perindopril [D03.633.100.473.766]
Skatole [D03.633.100.473.808]
Sporidesmins [D03.633.100.473.840]
Sunitinib [D03.633.100.473.877]
Tropisetron [D03.633.100.473.896]
Tryptamines [D03.633.100.473.914]
Vemurafenib [D03.633.100.473.936]
Vilazodone Hydrochloride [D03.633.100.473.957]
Expand All
Collapse All
Vemurafenib
Preferred
Concept UI
M0558887
Scope Note
An indole sulfonamide compound and inhibitor of
BRAF KINASES
that is used for the treatment of unresectable or metastatic
MELANOMA
.
Terms
Vemurafenib
Preferred Term
Term UI
T000939933
Date
01/31/2018
LexicalTag
NON
ThesaurusID
PLX4032
Narrower
Concept UI
M0548744
Terms
PLX4032
Preferred Term
Term UI
T775314
Date
08/02/2010
LexicalTag
LAB
ThesaurusID
NLM (2010)
PLX 4032
Term UI
T823188
Date
06/08/2012
LexicalTag
LAB
ThesaurusID
NLM (2012)
Zelboraf
Narrower
Concept UI
M0574188
Terms
Zelboraf
Preferred Term
Term UI
T823106
Date
06/07/2012
LexicalTag
TRD
ThesaurusID
NLM (2012)
R05185426
Narrower
Concept UI
M000623498
Terms
R05185426
Preferred Term
Term UI
T775316
Date
08/02/2010
LexicalTag
LAB
ThesaurusID
NLM (2010)
RG7204
Narrower
Concept UI
M000623499
Terms
RG7204
Preferred Term
Term UI
T775315
Date
08/02/2010
LexicalTag
LAB
ThesaurusID
NLM (2010)
RG-7204
Term UI
T000911560
Date
11/08/2016
LexicalTag
LAB
ThesaurusID
NLM (2017)
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