MeSH Browser

MeSH Heading: Proto-Oncogene Proteins B-raf
Tree Number(s): D08.811.913.696.620.682.700.559.842.374; D12.776.476.563.554.842.437; D12.776.624.664.700.204.200
Unique ID: D048493
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048493
Scope Note: A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
Entry Term(s): B-raf Kinase; B-raf Kinases; BRAF Kinase; BRAF Kinases; Proto-Oncogene Protein B-raf
Registry Numbers: EC 2.7.11.1
Previous Indexing: Proto-Oncogene Proteins c-raf (1988-2004)
Public MeSH Note: 2005; PROTO-ONCOGENE PROTEIN B-RAF was indexed under PROTO-OCOGENES C-RAF 2001-2004
History Note: 2005(2001)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029573
Registry Numbers: EC 2.7.11.1
Scope Note: A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
Terms: Proto-Oncogene Proteins B-raf Preferred Term
Term UI T574629
Date02/27/2004
LexicalTag NON
ThesaurusID NLM (2005); B-raf Kinase
Term UI T000998637
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); BRAF Kinase
Term UI T000998638
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Proto-Oncogene Protein B-raf
Term UI T059315
Date02/24/1997
LexicalTag NON
ThesaurusID NLM (2005); B-raf Kinases
Term UI T574630
Date02/27/2004
LexicalTag NON
ThesaurusID NLM (2005); BRAF Kinases
Term UI T591537
Date06/16/2004
LexicalTag NON
ThesaurusID NLM (2005)

Proto-Oncogene Proteins B-raf MeSH Descriptor Data 2025