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Proto-Oncogene Proteins c-raf MeSH Descriptor Data 2025


MeSH Heading
Proto-Oncogene Proteins c-raf
Tree Number(s)
D08.811.913.696.620.682.700.559.842.500
D12.776.476.563.554.842.500
D12.776.624.664.700.204.500
Unique ID
D019908
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019908
Scope Note
A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
Entry Term(s)
Kinase Raf-1
Kinase p74(raf-1)
Proto-Oncogene Protein c-raf
c-raf Kinases
c-raf Proteins
cRaf1 Kinase
raf-1 Kinase
Registry Numbers
EC 2.7.11.1
Previous Indexing
Protein-Serine-Threonine Kinases (1993-1997)
Proto-Oncogene Proteins (1986-1997)
See Also
Oncogene Proteins v-raf
Public MeSH Note
1998; PROTO-ONCOGENE PROTEIN MIL (now PROTO-ONCOGENE PROTEINS C-RAF) was indexed under PROTEIN-SERINE-THEONINE KINASES 1993-1997 & PROTO-ONCOGENE PROTEINS 1986-1997; CRAF1 KINASE was indexed under PROTO-ONCOGENE PROTEINS C-RAF 1993-2004
History Note
1998 (1986)
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2021/05/21
Proto-Oncogene Proteins c-raf Preferred
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