MeSH Browser

MeSH Heading: Multiple Carboxylase Deficiency
Tree Number(s): C16.320.565.100.620; C16.320.565.202.720; C18.452.648.100.620; C18.452.648.202.720
Unique ID: D009100
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009100
Scope Note: A deficiency in the activities of biotin-dependent enzymes (propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and PYRUVATE CARBOXYLASE) due to one of two defects in BIOTIN metabolism. The neonatal form is due to HOLOCARBOXYLASE SYNTHETASE DEFICIENCY. The late-onset form is due to BIOTINIDASE DEFICIENCY.
Entry Version: MULTIPLE CARBOXYLASE DEFIC
Entry Term(s): Carboxylase Deficiency, Combined; Carboxylase Deficiency, Multiple; Combined Carboxylase Deficiency; Deficiency, Combined Carboxylase; Deficiency, Multiple Carboxylase
Previous Indexing: specific enzyme (1966-1974); specific enzyme/deficiency (1975-1986)
See Also: Biotin
Public MeSH Note: 87
History Note: 87
Date Established: 1987/01/01
Date of Entry: 1986/04/18
Revision Date: 2006/07/05

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Multiple Carboxylase Deficiency MeSH Descriptor Data 2024