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Hyperhomocysteinemia MeSH Descriptor Data 2022


MeSH Heading
Hyperhomocysteinemia
Tree Number(s)
C16.320.565.100.480
C18.452.603.378
C18.452.648.100.480
C18.654.521.500.133.699.418
Unique ID
D020138
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020138
Scope Note
Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 μmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.
Entry Term(s)
NLM Classification #
QU 265.5.A5
Previous Indexing
Homocysteine/blood (1991-1998)
Public MeSH Note
1999
History Note
1999
Date Established
1999/01/01
Date of Entry
1998/06/10
Revision Date
2009/07/06
Hyperhomocysteinemia Preferred
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