MeSH Browser

MeSH Heading: Novobiocin
Tree Number(s): D03.383.663.283.446.139.500; D03.633.100.150.446.139.500; D09.408.554
Unique ID: D009675
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009675
Scope Note: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Entry Term(s): Crystallinic Acid; Novobiocin Calcium; Novobiocin Sodium; Novobiocin, Monosodium Salt; Streptonivicin
Pharm Action: Anti-Bacterial Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Related Numbers: 1476-53-5; 303-81-1; 4309-70-0; Q9S9NQ5YIY; RHW5BU180N
CAS Type 1 Name: Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0015020
Related Numbers: 1476-53-5; 303-81-1; 4309-70-0; Q9S9NQ5YIY; RHW5BU180N
Scope Note: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Terms: Novobiocin Preferred Term
Term UI T028766
Date01/01/1999
LexicalTag NON
ThesaurusID; Crystallinic Acid
Term UI T028765
Date04/28/1977
LexicalTag NON
ThesaurusID UNK (19XX); Streptonivicin
Term UI T028767
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX)

Novobiocin MeSH Descriptor Data 2024