NLM Logo

Pheochromocytoma MeSH Descriptor Data 2024

MeSH Heading
Tree Number(s)
Unique ID
RDF Unique Identifier
benign or malignant; coord IM with usually ADRENAL GLAND NEOPLASMS (IM)
Scope Note
A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Entry Term(s)
Pheochromocytoma, Extra-Adrenal
See Also
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia Type 2b
Date Established
Date of Entry
Revision Date
Pheochromocytoma Preferred
Pheochromocytoma, Extra-Adrenal Narrower
page delivered in 0.153s