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Podophyllotoxin MeSH Descriptor Data 2023


MeSH Heading
Podophyllotoxin
Tree Number(s)
D02.455.426.559.389.140.450.777
D02.455.426.559.847.638.960.675
D04.615.638.960.675
Unique ID
D011034
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011034
Annotation
/biosyn permitted if by plant
Scope Note
A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
Entry Term(s)
CPH86
Condyline
Condylox
Epipodophyllotoxin
Podocon-25
Podofilm
Podofilox
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer
Wartec
Warticon
Pharm Action
Antineoplastic Agents, Phytogenic
Keratolytic Agents
Tubulin Modulators
Registry Number
L36H50F353
Related Numbers
4375-06-8
4375-07-9
477-47-4
518-28-5
55568-79-1
CAS Type 1 Name
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
Previous Indexing
Alkaloids (1966-1972)
Antineoplastic Agents (1966-1972)
Public MeSH Note
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975
Online Note
use PODOPHYLLOTOXIN to search EPIPODOPHYLLOTOXIN 1975
History Note
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/01
Podophyllotoxin Preferred
Condylox Narrower
CPH86 Related
Epipodophyllotoxin Related
Podocon-25 Narrower
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer Narrower
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer Narrower
Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer Narrower
Wartec Narrower
Condyline Narrower
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer Narrower
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