MeSH Browser

MeSH Heading: Quinine
Tree Number(s): D03.132.206.719; D03.605.687.762; D03.633.100.810.762
Unique ID: D011803
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011803
Annotation: /biosyn permitted if by plant
Scope Note: An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Entry Term(s): Biquinate; Legatrim; Myoquin; Quinamm; Quinbisan; Quinbisul; Quindan; Quinimax; Quinine Bisulfate; Quinine Hydrochloride; Quinine Lafran; Quinine Sulfate; Quinine Sulphate; Quinine-Odan; Quinoctal; Quinson; Quinsul; Strema; Surquina
Pharm Action: Antimalarials
Muscle Relaxants, Central
Analgesics, Non-Narcotic
Registry Numbers: A7V27PHC7A; M201HC068W; 711S8Y0T33; KF7Z0E0Q2B; 0
Related Numbers: 130-95-0; 711S8Y0T33; KF7Z0E0Q2B; M201HC068W
CAS Type 1 Name: Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24