MeSH Browser

MeSH Heading: Saquinavir
Tree Number(s): D03.633.100.531.770; D03.633.100.810.900
Unique ID: D019258
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019258
Scope Note: An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.
Entry Term(s): Invirase; Ro 31-8959; Saquinavir Mesylate; Saquinavir Monomethanesulfonate; Saquinivir
Pharm Action: HIV Protease Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Numbers: L3JE09KZ2F; UHB9Z3841A; 0
Related Numbers: 127779-20-8; 149845-06-7; UHB9Z3841A
Previous Indexing: HIV Protease/antagonists & inhibitors (1990-1992); Isoquinolines (1993-1996); Quinolines (1993-1996)
Public MeSH Note: 97; SAQUINAVIR was indexed under ISOQUINOLINES & QUINOLINES 1993-96 and HIV PROTEASE/antagonists & inhibitors 1990-92
Online Note: use SAQUINAVIR (NM) to search SAQUINAVIR 1990-96
History Note: 97; was SAQUINAVIR (NM) 1990-96
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Saquinavir MeSH Descriptor Data 2025