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Palonosetron MeSH Descriptor Data 2022


MeSH Heading
Palonosetron
Tree Number(s)
D03.605.687.319
D03.633.100.531.629
Unique ID
D000077924
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077924
Scope Note
Isoquinoline and quinuclidine derivative that acts as a 5-HT3 RECEPTOR antagonist. It is used in the prevention of nausea and vomiting induced by cytotoxic chemotherapy, and for the prevention of post-operative nausea and vomiting.
Entry Term(s)
2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one
2-QHBIQO
Aloxi
Palonosetron Hydrochloride
Palonosetron, (3R)-
Palonosetron, (R-(R*,R*))-isomer
Palonosetron, (R-(R*,S*))-isomer
Palonosetron, (S-(R*,S*))-isomer
RS 25233-197
RS 25233-198
RS 25259
RS 25259-197
RS 25259-198
RS-25233-197
RS-25233-198
RS-25259
RS-25259-197
RS-25259-198
Pharm Action
Antiemetics
Serotonin 5-HT3 Receptor Antagonists
Registry Number
5D06587D6R
Related Numbers
135729-61-2
135729-73-6
149653-99-6
149654-00-2
23310D4I19
2UCB21ER4V
CAS Type 1 Name
1H-Benz(de)isoquinolin-1-one, 2-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-, (3aS)-
Public MeSH Note
2019; PALONOSETRON was indexed under ISOQUINOLINES and QUINUCLIDINES 1993-2018
History Note
2019 (1993)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/05/21
Palonosetron Preferred
Palonosetron, (R-(R*,R*))-isomer Narrower
Palonosetron, (R-(R*,S*))-isomer Narrower
RS 25259-198 Narrower
2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one Broader
RS 25233-198 Narrower
RS 25259 Narrower
RS 25259-197 Narrower
Aloxi Narrower
Palonosetron, (S-(R*,S*))-isomer Narrower
Palonosetron Hydrochloride Narrower
RS 25233-197 Narrower
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