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Sphingomyelin Phosphodiesterase MeSH Descriptor Data 2023


MeSH Heading
Sphingomyelin Phosphodiesterase
Tree Number(s)
D08.811.277.352.640.750
Unique ID
D013108
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013108
Annotation
/defic: consider also NIEMANN-PICK DISEASE
Scope Note
An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.
Entry Term(s)
Sphingomyelin Cholinephosphohydrolase
Sphingomyelin Cleaving Enzyme
Sphingomyelinase
Sphingomyelinase C
Registry Number
EC 3.1.4.12
CAS Type 1 Name
Sphingomyelin cholinephosphohydrolase
Previous Indexing
Phosphodiesterases (1973-1974)
Sphingomyelins (1973-1974)
See Also
Niemann-Pick Diseases
Public MeSH Note
91; was see under PHOSPHODIESTERASES 1975-90
History Note
91(75); was see under PHOSPHODIESTERASES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2003/07/09
Sphingomyelin Phosphodiesterase Preferred
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