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Phosphodiesterase I MeSH Descriptor Data 2022


MeSH Heading
Phosphodiesterase I
Tree Number(s)
D08.811.277.352.640.430
Unique ID
D043264
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D043264
Scope Note
A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis.
Entry Term(s)
5'-Exonuclease
5'-Nucleotidephosphodiesterase
Alkaline Phosphodiesterase
Alkaline Phosphodiesterase I
Oligonucleate 5'-Nucleotidohydrolase
Orthophosphoric Diester Phosphohydrolase
Registry Number
EC 3.1.4.1
Related Numbers
9025-82-5
Previous Indexing
Phosphoric Diester Hydrolases (1978-2003)
Public MeSH Note
2004; PHOSPHODIESTERASE I was indexed under PHOSPHORIC DIESTER HYDROLASES 1981-2003, under NUCLEOTIDES 1978-1980
History Note
2004; use PHOSPHODIESTERASE I (NM) 1980-2003
Date Established
2004/01/01
Date of Entry
2003/07/09
Phosphodiesterase I Preferred
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