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Tryptophan Oxygenase MeSH Descriptor Data 2022


MeSH Heading
Tryptophan Oxygenase
Tree Number(s)
D08.811.682.690.416.722
Unique ID
D014366
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014366
Scope Note
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Entry Term(s)
TDO Dioxygenase
Tryptophan 2,3-Dioxygenase
Tryptophan Pyrrolase
Registry Number
EC 1.13.11.11
CAS Type 1 Name
L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
See Also
Tryptophan Hydroxylase
Public MeSH Note
68
History Note
68(65)
Date Established
1968/01/01
Date of Entry
1999/01/01
Revision Date
2005/06/30
Tryptophan Oxygenase Preferred
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