MeSH Browser

MeSH Heading: Fibrin Tissue Adhesive
Tree Number(s): D12.776.124.270.305
Unique ID: D015718
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015718
Scope Note: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
Entry Term(s): Autologous Fibrin Tissue Adhesive; Beriplast; Crosseal; Fibrin Adhesive; Fibrin Glue; Fibrin Klebe System Immuno; Fibrin Seal; Fibrin Sealant; Fibrin Sealant System; Fibrin Sealant, Human; Fibrinogen Adhesive; Tisseel; Tissel; Tissucol; Transglutine
Pharm Action: Hemostatics
Tissue Adhesives
Previous Indexing: Factor VIII (1966-1989); Fibrinogen (1966-1969); Hemostatics (1966-1989); Thrombin (1966-1989)
See Also: Platelet-Rich Fibrin
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/05/15
Revision Date: 2016/10/14

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0024100
Scope Note: An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
Terms: Fibrin Tissue Adhesive Preferred Term
Term UI T046598
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Fibrin Adhesive
Term UI T046592
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Fibrin Glue
Term UI T046593
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Autologous Fibrin Tissue Adhesive
Term UI T046590
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Fibrin Sealant System
Term UI T046597
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Fibrinogen Adhesive
Term UI T046599
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Fibrin Sealant
Term UI T046596
Date02/17/1989
LexicalTag NON
ThesaurusID NLM (1990)

Fibrin Tissue Adhesive MeSH Descriptor Data 2024