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Fibrinogen MeSH Descriptor Data 2022


MeSH Heading
Fibrinogen
Tree Number(s)
D12.776.124.050.250
D12.776.124.125.500
D12.776.811.300
D23.119.490
Unique ID
D005340
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005340
Annotation
a blood coag factor: do not confuse entry term FACTOR I with COMPLEMENT FACTOR I
Scope Note
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Entry Term(s)
Blood Coagulation Factor I
Coagulation Factor I
Factor I
gamma-Fibrinogen
Registry Number
9001-32-5
CAS Type 1 Name
Fibrinogens
See Also
Coagulants
Hemostatics
Entry Combination
deficiency:Afibrinogenemia
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/28
Fibrinogen Preferred
gamma-Fibrinogen Narrower
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