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Platelet Factor 4 MeSH Descriptor Data 2022


MeSH Heading
Platelet Factor 4
Tree Number(s)
D12.644.276.374.200.120.900
D12.776.124.125.720
D12.776.467.374.200.120.900
D23.119.940
D23.125.300.120.900
D23.469.200.120.900
D23.529.374.200.120.900
Unique ID
D010978
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010978
Scope Note
A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Entry Term(s)
Antiheparin Factor
CXCL4 Chemokine
Chemokine CXCL4
Heparin Neutralizing Protein
PF4 (Platelet Factor 4)
gamma-Thromboglobulin
Pharm Action
Coagulants
Registry Number
37270-94-3
CAS Type 1 Name
Blood platelet factor 4
Previous Indexing
Blood Coagulation Factors (1973-1975)
Blood Platelets (1974-1975)
Glycoproteins (1974-1975)
Public MeSH Note
84; was see under BLOOD COAGULATION FACTORS 1976-83
History Note
84(76); was see under BLOOD COAGULATION FACTORS 1976-83
Date Established
1984/01/01
Date of Entry
1975/07/25
Revision Date
2007/07/09
Platelet Factor 4 Preferred
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