NLM Logo

Giant Cells, Langhans MeSH Descriptor Data 2022


MeSH Heading
Giant Cells, Langhans
Tree Number(s)
A11.329.372.380
A11.500.380
A11.627.482.380
A11.733.397.380
A15.382.670.522.380
A15.382.680.397.380
Unique ID
D015744
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015744
Annotation
do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS
Scope Note
Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.
Entry Term(s)
Langhans Giant Cells
Langhans-Type Giant Cells
Previous Indexing
Granuloma, Giant Cell (1977-1989)
Macrophages (1966-1989)
Public MeSH Note
91; was see under GIANT CELLS 1990
History Note
91(90); was see under GIANT CELLS 1990
Date Established
1991/01/01
Date of Entry
1989/04/07
Revision Date
2018/06/30
Giant Cells, Langhans Preferred
page delivered in 0.142s