MeSH Browser

MeSH Heading: Codon, Initiator
Tree Number(s): D13.444.735.544.355.225; G05.360.335.355.225; G05.360.340.024.340.137.190.225
Unique ID: D018387
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018387
Scope Note: A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.
Entry Term(s): Codon, Initiation; Codon, Start; Initiator Codon; Start Codon
Previous Indexing: Codon (1975-1994)
See Also: Peptide Chain Initiation, Translational; Protein Biosynthesis
Public MeSH Note: 95
History Note: 95
Date Established: 1995/01/01
Date of Entry: 1994/06/03
Revision Date: 2008/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0027614
Scope Note: A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.
Terms: Codon, Initiator Preferred Term
Term UI T054824
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1995); Codon, Initiation
Term UI T054822
Date09/14/1993
LexicalTag NON
ThesaurusID NLM (1995); Initiator Codon
Term UI T054823
Date01/06/1994
LexicalTag NON
ThesaurusID NLM (1995); Codon, Start
Term UI T054825
Date09/14/1993
LexicalTag NON
ThesaurusID NLM (1995); Start Codon
Term UI T498964
Date06/18/2002
LexicalTag NON
ThesaurusID NLM (2003)

Codon, Initiator MeSH Descriptor Data 2024