MeSH Browser

MeSH Heading: Sneddon Syndrome
Tree Number(s): C10.228.140.300.750; C14.907.253.774; C17.800.862.775
Unique ID: D018860
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018860
Annotation: do not confuse with SNEDDON-WILKINSON DISEASE see SKIN DISEASES, VESICULOBULLOUS
Scope Note: A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of LIVEDO RETICULARIS, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60). Mutations in the CECR1 gene (ADA2 protein, human) are associated with Sneddon syndrome.
Entry Term(s): Livedo Reticularis And Cerebrovascular Accidents; Livedo Reticularis, Systemic Involvement; Sneddon-Champion Syndrome
Previous Indexing: Cerebrovascular Disorders (1983-1995); Skin (1979-1983); Skin Diseases, Vascular (1993-1995)
Public MeSH Note: 1996
History Note: 1996
Date Established: 1996/01/01
Date of Entry: 1994/12/27
Revision Date: 2023/06/05

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0028214
Scope Note: A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of LIVEDO RETICULARIS, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60). Mutations in the CECR1 gene (ADA2 protein, human) are associated with Sneddon syndrome.
Terms: Sneddon Syndrome Preferred Term
Term UI T056213
Date01/01/1999
LexicalTag EPO
ThesaurusID; Livedo Reticularis, Systemic Involvement
Term UI T370325
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Sneddon-Champion Syndrome
Term UI T056212
Date07/12/1994
LexicalTag EPO
ThesaurusID NLM (1996); Livedo Reticularis And Cerebrovascular Accidents
Term UI T812296
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013)

Sneddon Syndrome MeSH Descriptor Data 2024