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Sneddon Syndrome MeSH Descriptor Data 2025


MeSH Heading
Sneddon Syndrome
Tree Number(s)
C10.228.140.300.750
C14.907.253.774
C17.800.862.775
Unique ID
D018860
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018860
Annotation
do not confuse with SNEDDON-WILKINSON DISEASE see SKIN DISEASES, VESICULOBULLOUS
Scope Note
A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of LIVEDO RETICULARIS, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60). Mutations in the CECR1 gene (ADA2 protein, human) are associated with Sneddon syndrome.
Entry Term(s)
Livedo Reticularis And Cerebrovascular Accidents
Livedo Reticularis, Systemic Involvement
Sneddon-Champion Syndrome
Previous Indexing
Cerebrovascular Disorders (1983-1995)
Skin (1979-1983)
Skin Diseases, Vascular (1993-1995)
Public MeSH Note
1996
History Note
1996
Date Established
1996/01/01
Date of Entry
1994/12/27
Revision Date
2023/06/05
Sneddon Syndrome Preferred
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