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Paraneoplastic Cerebellar Degeneration MeSH Descriptor Data 2022


MeSH Heading
Paraneoplastic Cerebellar Degeneration
Tree Number(s)
C04.588.614.550.650
C04.730.856.650
C10.228.140.252.620
C10.574.781.700
Unique ID
D020362
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020362
Annotation
coord with precoord organ/neopl term + histol type
Scope Note
Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Entry Version
PARANEOPL CEREBELLAR DEGENERATION
Entry Term(s)
Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration
Cerebellar Degeneration, Paraneoplastic
Cerebellar Syndrome, Paraneoplastic
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Paraneoplastic Cerebellar Syndrome
Previous Indexing
Cerebellar Ataxia (1975-1999)
Paraneoplastic Syndromes (1980-1999)
Public MeSH Note
2000
History Note
2000
Date Established
2000/01/01
Date of Entry
1999/11/04
Revision Date
2009/07/06
Paraneoplastic Cerebellar Degeneration Preferred
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated Narrower
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