MeSH Browser

MeSH Heading: Phosphofructokinase-1, Muscle Type
Tree Number(s): D08.811.913.696.620.225.850.500.500
Unique ID: D025203
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D025203
Scope Note: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Entry Term(s): 6-Phosphofructokinase, Muscle Type; Phosphofructo-1-kinase Isozyme A
Registry Number: EC 2.7.1.-
Previous Indexing: 6-Phosphofructokinase (1977-2001)
Public MeSH Note: 2002
History Note: 2002
Entry Combination: deficiency:Glycogen Storage Disease Type VII
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2005/07/25

Entry Combination: deficiency:Glycogen Storage Disease Type VII
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0373928
Registry Number: EC 2.7.1.-
Scope Note: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Terms: Phosphofructokinase-1, Muscle Type Preferred Term
Term UI T430208
Date12/04/2000
LexicalTag NON
ThesaurusID NLM (2002); Phosphofructo-1-kinase Isozyme A
Term UI T430183
Date12/04/2000
LexicalTag NON
ThesaurusID NLM (2002); 6-Phosphofructokinase, Muscle Type
Term UI T430182
Date12/04/2000
LexicalTag NON
ThesaurusID NLM (2002)

Phosphofructokinase-1, Muscle Type MeSH Descriptor Data 2024