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Phosphofructokinase-1 MeSH Descriptor Data 2022


MeSH Heading
Phosphofructokinase-1
Tree Number(s)
D08.811.913.696.620.225.850.500
Unique ID
D010732
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010732
Annotation
general or unspecified; prefer specifics
Scope Note
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
Entry Term(s)
6-Phosphofructo-1-kinase
6-Phosphofructokinase
Fructose-6-P 1-Kinase
Fructose-6-phosphate 1-Phosphotransferase
Registry Number
EC 2.7.1.11
Related Numbers
9001-80-3
CAS Type 1 Name
ATP:D-fructose-6-phosphate 1-phosphotransferase
See Also
Glycogen Storage Disease Type VII
Phosphofructokinase-2
Public MeSH Note
2002; see 6-PHOSPHOFRUCTOKINASE 1993-2001, see PHOSPHOFRUCTOKINASE 1965-1992
History Note
2002
Date Established
1965/01/01
Date of Entry
1999/01/01
Revision Date
2009/07/13
Phosphofructokinase-1 Preferred
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