NLM Logo

RNA Interference MeSH Descriptor Data 2022


MeSH Heading
RNA Interference
Tree Number(s)
G05.308.203.374.790
Unique ID
D034622
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D034622
Scope Note
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Entry Term(s)
Co-Suppression
Cosuppression
Gene Silencing, Post-Transcriptional
Post-Transcriptional Gene Silencing
Posttranscriptional Gene Silencing
RNA Silencing
RNAi
NLM Classification #
QU 58.7
See Also
RNA-Induced Silencing Complex
RNA, Small Interfering
RNAi Therapeutics
Public MeSH Note
2003
History Note
2003
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/06/17
RNA Interference Preferred
Cosuppression Related
page delivered in 0.219s