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RNA-Induced Silencing Complex MeSH Descriptor Data 2022


MeSH Heading
RNA-Induced Silencing Complex
Tree Number(s)
D08.811.277.352.355.350.810
D08.811.277.352.700.350.810
D12.776.157.725.500.906
D12.776.664.962.500.906
Unique ID
D034743
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D034743
Scope Note
A multicomponent, ribonucleoprotein complex comprised of one of the family of ARGONAUTE PROTEINS and the "guide strand" of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating gene expression are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA).
Entry Version
RNA IND SILENCING COMPLEX
Entry Term(s)
RISC Multicomponent Nuclease
Registry Number
0
Previous Indexing
Endoribonucleases (2001-2002)
See Also
RNA Interference
RNA, Small Interfering
Public MeSH Note
2003; RNA-INDUCED SILENCING COMPLEX was indexed under RIBONUCLEOPROTEINS 2001-2002
History Note
2003; use RNA-INDUCED SILENCING COMPLEX (NM) 2001-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2011/06/24
RNA-Induced Silencing Complex Preferred
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