Receptor, EphA5 MeSH Descriptor Data 2024

MeSH Heading: Receptor, EphA5
Tree Number(s): D08.811.913.696.620.682.725.400.850.250; D12.776.476.568.400.850.250; D12.776.543.750.630.500.250
Unique ID: D036123
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D036123
Scope Note: An eph family receptor found primarily in differentiated neuronal tissues. Several isoforms of EphA5 receptor occur due to multiple alternative RNA splicing. The protein is prominently expressed in the NEURONS of the LIMBIC SYSTEM during development and throughout adult life, suggesting its role in the plasticity of limbic structure and function.
Entry Version: RECEPT EPHA5
Entry Term(s): Brain-Specific Kinase; EphA5 Protein; EphA5 Receptor; bsk Tyrosine Kinase
Registry Numbers: EC 2.7.10.1
Previous Indexing: Receptor Protein-Tyrosine Kinases (1994-2002)
Public MeSH Note: 2003; BRAIN-SPECIFIC KINASE & CEK7 PROTEIN (now RECEPTOR, EPHA5) were indexed under RECEPTOR PROTEIN-TYROSINE KINASES 1994-2002; EPHA5 PROTEIN (now RECEPTOR, EPHA5 ) were indexed under RECEPTOR PROTEIN-TYROSINE KINASES 1998-2002
History Note: 2003; use RECEPTOR, EPHA5 (NM) 1994-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
        
        Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
        
        Receptors, Eph Family [D08.811.913.696.620.682.725.400.850]
        
        Receptor, EphA1 [D08.811.913.696.620.682.725.400.850.050]
        
        Receptor, EphA2 [D08.811.913.696.620.682.725.400.850.100]
        
        Receptor, EphA3 [D08.811.913.696.620.682.725.400.850.150]
        
        Receptor, EphA4 [D08.811.913.696.620.682.725.400.850.200]
        
        Receptor, EphA5 [D08.811.913.696.620.682.725.400.850.250]
        
        Receptor, EphA6 [D08.811.913.696.620.682.725.400.850.300]
        
        Receptor, EphA7 [D08.811.913.696.620.682.725.400.850.400]
        
        Receptor, EphA8 [D08.811.913.696.620.682.725.400.850.500]
        
        Receptor, EphB1 [D08.811.913.696.620.682.725.400.850.600]
        
        Receptor, EphB2 [D08.811.913.696.620.682.725.400.850.650]
        
        Receptor, EphB3 [D08.811.913.696.620.682.725.400.850.700]
        
        Receptor, EphB4 [D08.811.913.696.620.682.725.400.850.750]
        
        Receptor, EphB5 [D08.811.913.696.620.682.725.400.850.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein-Tyrosine Kinases [D12.776.476.568]
      - Receptor Protein-Tyrosine Kinases [D12.776.476.568.400]
        
        Receptors, Eph Family [D12.776.476.568.400.850]
        
        Receptor, EphA1 [D12.776.476.568.400.850.050]
        
        Receptor, EphA2 [D12.776.476.568.400.850.100]
        
        Receptor, EphA3 [D12.776.476.568.400.850.150]
        
        Receptor, EphA4 [D12.776.476.568.400.850.200]
        
        Receptor, EphA5 [D12.776.476.568.400.850.250]
        
        Receptor, EphA6 [D12.776.476.568.400.850.300]
        
        Receptor, EphA7 [D12.776.476.568.400.850.400]
        
        Receptor, EphA8 [D12.776.476.568.400.850.500]
        
        Receptor, EphB1 [D12.776.476.568.400.850.600]
        
        Receptor, EphB2 [D12.776.476.568.400.850.650]
        
        Receptor, EphB3 [D12.776.476.568.400.850.700]
        
        Receptor, EphB4 [D12.776.476.568.400.850.750]
        
        Receptor, EphB5 [D12.776.476.568.400.850.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
        
        Receptors, Eph Family [D12.776.543.750.630.500]
        
        Receptor, EphA1 [D12.776.543.750.630.500.050]
        
        Receptor, EphA2 [D12.776.543.750.630.500.100]
        
        Receptor, EphA3 [D12.776.543.750.630.500.150]
        
        Receptor, EphA4 [D12.776.543.750.630.500.200]
        
        Receptor, EphA5 [D12.776.543.750.630.500.250]
        
        Receptor, EphA6 [D12.776.543.750.630.500.300]
        
        Receptor, EphA7 [D12.776.543.750.630.500.350]
        
        Receptor, EphA8 [D12.776.543.750.630.500.400]
        
        Receptor, EphB1 [D12.776.543.750.630.500.450]
        
        Receptor, EphB2 [D12.776.543.750.630.500.500]
        
        Receptor, EphB3 [D12.776.543.750.630.500.687]
        
        Receptor, EphB4 [D12.776.543.750.630.500.781]
        
        Receptor, EphB5 [D12.776.543.750.630.500.875]
        
        Receptor, EphB6 [D12.776.543.750.630.500.937]

Receptor, EphA5 Preferred

Concept UI: M0290346
Registry Numbers: EC 2.7.10.1
Scope Note: An eph family receptor found primarily in differentiated neuronal tissues. Several isoforms of EphA5 receptor occur due to multiple alternative RNA splicing. The protein is prominently expressed in the NEURONS of the LIMBIC SYSTEM during development and throughout adult life, suggesting its role in the plasticity of limbic structure and function.
Terms: Receptor, EphA5 Preferred Term
Term UI T482200
Date02/15/2002
LexicalTag ACX
ThesaurusID NLM (2003); bsk Tyrosine Kinase
Term UI T259473
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); Brain-Specific Kinase
Term UI T259474
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); EphA5 Protein
Term UI T320351
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); EphA5 Receptor
Term UI T475804
Date01/04/2002
LexicalTag ACX
ThesaurusID NLM (2003)

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