A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
Entry Term(s)
CstF Protein
Previous Indexing
RNA-Binding Proteins (1992-2002)
Public MeSH Note
2003; CLEAVAGE STIMULATION FACTOR was indexed under RNA-BINDING PROTEINS 1992-2002
History Note
2003; for CLEAVAGE STIMULATION FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002
A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.