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Neuropilin-2 MeSH Descriptor Data 2023


MeSH Heading
Neuropilin-2
Tree Number(s)
D12.776.543.750.590.750
Unique ID
D039943
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D039943
Scope Note
Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.
Entry Term(s)
NRP2 Protein
Npn-2 Protein
Registry Number
0
Previous Indexing
Nerve Tissue Proteins (1998-2002)
Public MeSH Note
2003; NPN-2 PROTEIN was indexed under NERVE TISSUE PROTEINS 1998-2002
History Note
2003; for NPN-2 PROTEIN use NEUROPILIN-1 1998-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/05/31
Neuropilin-2 Preferred
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