MeSH Browser

MeSH Heading: Semaphorin-3A
Tree Number(s): D12.644.276.923.374; D12.776.467.923.374; D23.529.923.374
Unique ID: D040121
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D040121
Scope Note: The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
Entry Term(s): Collapsin; Collapsin-1; Collapsing Factor; Sem D; Sema3A; Semaphorin 3A; Semaphorin D
Registry Numbers: 0
Previous Indexing: Glycoproteins (1993-2002)
Public MeSH Note: 2003; COLLAPSIN (now SEMAPHORIN 3A) was indexed under GLYCOPROTEINS 1993-2002
History Note: 2003; use SEMAPHORIN 3A (NM) 1994-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0222872
Registry Numbers: 0
Scope Note: The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
Terms: Semaphorin-3A Preferred Term
Term UI T433687
Date01/20/2001
LexicalTag NON
ThesaurusID NLM (2003); Sem D
Term UI T252873
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); Semaphorin D
Term UI T252875
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Collapsin
Term UI T252877
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Sema3A
Term UI T433685
Date01/20/2001
LexicalTag ACR
ThesaurusID NLM (2003); Semaphorin 3A
Term UI T433686
Date01/20/2001
LexicalTag NON
ThesaurusID NLM (2003); Collapsing Factor
Term UI T252871
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Collapsin-1
Term UI T252870
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003)

Semaphorin-3A MeSH Descriptor Data 2025