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Receptor, Serotonin, 5-HT1D MeSH Descriptor Data 2023


MeSH Heading
Receptor, Serotonin, 5-HT1D
Tree Number(s)
D12.776.543.750.670.800.100.200
D12.776.543.750.695.800.100.200
D12.776.543.750.720.670.100.750
D12.776.543.750.720.850.100.200
Unique ID
D044346
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D044346
Scope Note
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
Entry Version
RECEPT SEROTONIN 5 HT1D
Entry Term(s)
5-HT(1D) Receptor
5-HT(1Dalpha) Receptor
5-HT1D Receptor
5-HT1Dalpha Receptor
5-Hydroxytryptamine1D Receptor
Receptor, Serotonin 1D
Receptor, Serotonin 1Dalpha
Serotonin 1D Alpha Receptor
Serotonin 1D Receptor
Serotonin 1D Receptors
Serotonin 1Dalpha Receptor
Serotonin 1Dalpha Receptors
Registry Number
0
Previous Indexing
Receptors, Serotonin (1996-2003)
Public MeSH Note
2004; SEROTONIN 1D RECEPTOR (now RECEPTOR, SEROTONIN, 5-HT1D) was indexed under RECEPTORS, SEROTONIN 1996-2003; SEROTONIN 1DALPHA RECEPTOR was indexed under RECEPTORS, SEROTONIN 1997-2003;
History Note
2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
Entry Combination
agonists:Serotonin 5-HT1 Receptor Agonists
antagonists & inhibitors:Serotonin 5-HT1 Receptor Antagonists
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2016/06/17
Receptor, Serotonin, 5-HT1D Preferred
5-HT(1Dalpha) Receptor Narrower
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