MeSH Browser

MeSH Heading: Mitogen-Activated Protein Kinase 10
Tree Number(s): D08.811.913.696.620.682.700.567.374.800; D12.776.476.563.567.374.800
Unique ID: D048057
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048057
Scope Note: A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.
Entry Term(s): JNK3 Mitogen Activated Protein Kinase; MAP Kinase p49(3F12); MAPK10 Mitogen-Activated Protein Kinase; Mitogen Activated Protein Kinase p49(3F12); Stress-Activated Protein Kinase JNK3; c-jun Kinase 3; c-jun N-Terminal Kinase 3; p49 3F12 Kinase; p49(3F12) SAP Kinase; p54-SAPK(beta)
Previous Indexing: Mitogen-Activated Protein Kinases (2000-2004); Protein-Serine-Threonine Kinases (1995-1999)
Public MeSH Note: 2005; MITOGEN-ACTIVATED PROTEIN KINASE 10 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004, under PROTEIN-SERINE-THREONINE KINASES 1995-1999
History Note: 2005(1995)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700]
        
        Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
        
        JNK Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567.374]
        
        Mitogen-Activated Protein Kinase 8 [D08.811.913.696.620.682.700.567.374.500]
        
        Mitogen-Activated Protein Kinase 9 [D08.811.913.696.620.682.700.567.374.750]
        
        Mitogen-Activated Protein Kinase 10 [D08.811.913.696.620.682.700.567.374.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein Serine-Threonine Kinases [D12.776.476.563]
      - Mitogen-Activated Protein Kinases [D12.776.476.563.567]
        
        JNK Mitogen-Activated Protein Kinases [D12.776.476.563.567.374]
        
        Mitogen-Activated Protein Kinase 8 [D12.776.476.563.567.374.500]
        
        Mitogen-Activated Protein Kinase 9 [D12.776.476.563.567.374.750]
        
        Mitogen-Activated Protein Kinase 10 [D12.776.476.563.567.374.800]

Mitogen-Activated Protein Kinase 10 Preferred

Concept UI: M0241808
Scope Note: A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.
Terms: Mitogen-Activated Protein Kinase 10 Preferred Term
Term UI T571717
Date02/06/2004
LexicalTag NON
ThesaurusID NLM (2005); c-jun Kinase 3
Term UI T271808
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); Mitogen Activated Protein Kinase p49(3F12)
Term UI T271809
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); p49 3F12 Kinase
Term UI T271810
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); p49(3F12) SAP Kinase
Term UI T271811
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); p54-SAPK(beta)
Term UI T271812
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2005); Stress-Activated Protein Kinase JNK3
Term UI T271813
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); c-jun N-Terminal Kinase 3
Term UI T571731
Date02/06/2004
LexicalTag NON
ThesaurusID NLM (2005); JNK3 Mitogen Activated Protein Kinase
Term UI T573449
Date02/19/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAP Kinase p49(3F12)
Term UI T271807
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); MAPK10 Mitogen-Activated Protein Kinase
Term UI T574117
Date02/24/2004
LexicalTag NON
ThesaurusID NLM (2005)

Mitogen-Activated Protein Kinase 10 MeSH Descriptor Data 2024