STAT2 Transcription Factor MeSH Descriptor Data 2024

MeSH Heading: STAT2 Transcription Factor
Tree Number(s): D12.644.360.024.303.500.750; D12.644.360.024.342.200; D12.776.157.057.061.500.750; D12.776.157.057.186.200; D12.776.260.513.249.750; D12.776.476.024.386.500.750; D12.776.476.024.430.200; D12.776.930.354.249.750; D12.776.930.840.200
Unique ID: D050795
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050795
Scope Note: A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
Entry Term(s): STAT2 Protein; Signal Transducer and Activator of Transcription 2; Transcription Factor STAT2
Public MeSH Note: 2006; STAT2 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1995-2005
History Note: 2006(1995)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
        
        Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
        
        STAT1 Transcription Factor [D12.644.360.024.303.500.500]
        
        STAT2 Transcription Factor [D12.644.360.024.303.500.750]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - STAT Transcription Factors [D12.644.360.024.342]
        
        STAT1 Transcription Factor [D12.644.360.024.342.100]
        
        STAT2 Transcription Factor [D12.644.360.024.342.200]
        
        STAT3 Transcription Factor [D12.644.360.024.342.300]
        
        STAT4 Transcription Factor [D12.644.360.024.342.400]
        
        STAT5 Transcription Factor [D12.644.360.024.342.500]
        
        STAT6 Transcription Factor [D12.644.360.024.342.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
        
        Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
        
        STAT1 Transcription Factor [D12.776.157.057.061.500.500]
        
        STAT2 Transcription Factor [D12.776.157.057.061.500.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - STAT Transcription Factors [D12.776.157.057.186]
        
        STAT1 Transcription Factor [D12.776.157.057.186.100]
        
        STAT2 Transcription Factor [D12.776.157.057.186.200]
        
        STAT3 Transcription Factor [D12.776.157.057.186.300]
        
        STAT4 Transcription Factor [D12.776.157.057.186.400]
        
        STAT5 Transcription Factor [D12.776.157.057.186.500]
        
        STAT6 Transcription Factor [D12.776.157.057.186.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
      - Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
        
        STAT1 Transcription Factor [D12.776.260.513.249.500]
        
        STAT2 Transcription Factor [D12.776.260.513.249.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
        
        Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.476.024.386.500]
        
        STAT1 Transcription Factor [D12.776.476.024.386.500.500]
        
        STAT2 Transcription Factor [D12.776.476.024.386.500.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - STAT Transcription Factors [D12.776.476.024.430]
        
        STAT1 Transcription Factor [D12.776.476.024.430.100]
        
        STAT2 Transcription Factor [D12.776.476.024.430.200]
        
        STAT3 Transcription Factor [D12.776.476.024.430.300]
        
        STAT4 Transcription Factor [D12.776.476.024.430.400]
        
        STAT5 Transcription Factor [D12.776.476.024.430.500]
        
        STAT6 Transcription Factor [D12.776.476.024.430.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
      - Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
        
        STAT1 Transcription Factor [D12.776.930.354.249.500]
        
        STAT2 Transcription Factor [D12.776.930.354.249.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - STAT Transcription Factors [D12.776.930.840]

STAT2 Transcription Factor Preferred

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