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STAT3 Transcription Factor MeSH Descriptor Data 2022


MeSH Heading
STAT3 Transcription Factor
Tree Number(s)
D12.644.360.024.342.300
D12.776.157.057.186.300
D12.776.476.024.430.300
D12.776.930.840.300
Unique ID
D050796
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050796
Scope Note
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Entry Term(s)
APRF Transcription Factor
Acute-Phase Response Factor
IL6-Response Factor
LIF-Response Factor
STAT3 Protein
STAT3a Transcription Factor
STAT3b Transcription Factor
Signal Transducer and Activator of Transcription 3
Stat3alpha Transcription Factor
Stat3beta Transcription Factor
Registry Number
0
See Also
src Homology Domains
Public MeSH Note
2006; STAT3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSACTIVATORS 1994-2005
History Note
2006
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/02/18
STAT3 Transcription Factor Preferred
STAT3b Transcription Factor Narrower
STAT3a Transcription Factor Narrower
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