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Cyclin-Dependent Kinase 4 MeSH Descriptor Data 2022


MeSH Heading
Cyclin-Dependent Kinase 4
Tree Number(s)
D08.811.913.696.620.682.700.646.500.875
D12.776.167.200.451
D12.776.476.563.646.500.875
Unique ID
D051358
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051358
Scope Note
Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.
Entry Term(s)
Cdk4 Cyclin-Dependent Kinase
Cdk4 Protein
Cdk4 Protein Kinase
Cell Division Protein Kinase 4
Cyclin D-Dependent Kinase CDK4
PSK-J3 Kinase
p34PSK-J3 Kinase
Registry Number
EC 2.7.11.22
Public MeSH Note
2006; CYCLIN-DEPENDENT KINASE 4 was indexed under CYCLIN-DEPENDENT KINASES & PROTO-ONCOGENE PROTEINS 2005, CELL CYCLE PROTEINS 1992-2004, PROTEIN SERINE THREONINE KINASES 1995, & under PROTEIN KINASES 1992-1994
History Note
2006(1992)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
Cyclin-Dependent Kinase 4 Preferred
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