NLM Logo

Protein Kinase C-alpha MeSH Descriptor Data 2024


MeSH Heading
Protein Kinase C-alpha
Tree Number(s)
D08.811.913.696.620.682.700.725.100
D12.776.476.563.725.100
Unique ID
D051571
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051571
Scope Note
A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.
Entry Term(s)
PKC-alpha Serine-Threonine Kinase
Protein Kinase C alpha
Protein Kinase C(alpha)
Registry Number
EC 2.7.11.13
Public MeSH Note
2006; PROTEIN KINASE C ALPHA was indexed under PROTEIN KINASE C 2004-2006, & under ISOENZYMES 1999-2003
History Note
2006(1999)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
Protein Kinase C-alpha Preferred
page delivered in 0.151s