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Protein Tyrosine Phosphatase, Non-Receptor Type 1 MeSH Descriptor Data 2025


MeSH Heading
Protein Tyrosine Phosphatase, Non-Receptor Type 1
Tree Number(s)
D08.811.277.352.650.775.300.100
D12.776.476.564.300.100
Unique ID
D054562
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054562
Scope Note
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Entry Term(s)
PTPase 1B
PTPase HA2
Protein Tyrosine Phosphatase 1B
Protein-Tyrosine Phosphatase HA2
Registry Numbers
EC 3.1.3.48
Previous Indexing
Protein Tyrosine Phosphatases (1991-2007)
Public MeSH Note
2008; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 was indexed under PROTEIN TYROSINE PHOSPHATASES 2000-2007, and under MEMBRANE PROTEINS & PROTEIN TYROSINE PHOSPHATASES 1999-2000; for PTPase 1B see PROTEIN-TYROSINE-PHOSPHATASE 1991-2007
History Note
2008
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2021/05/21
Protein Tyrosine Phosphatase, Non-Receptor Type 1 Preferred
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