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Protein Tyrosine Phosphatase, Non-Receptor Type 2 MeSH Descriptor Data 2025
A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.
Entry Term(s)
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform
Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform
T-Cell Protein Tyrosine Phosphatase
TC-PTP
TC45 Enzyme
TC45 Protein Tyrosine Phosphatase
TC48 Enzyme
TC48 Protein Tyrosine Phosphatase
TCPTP Enzyme
Registry Numbers
EC 3.1.3.48
EC 3.1.3.48
EC 3.1.3.48
Related Numbers
EC 3.1.3.48
Public MeSH Note
2008; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2 was indexed under PROTEIN TYROSINE PHOSPHATASE 1994-2007
A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.