Receptors, Purinergic P2X2 MeSH Descriptor Data 2024

MeSH Heading: Receptors, Purinergic P2X2
Tree Number(s): D12.776.157.530.400.400.750.200; D12.776.543.550.450.500.600.200; D12.776.543.585.400.500.600.200; D12.776.543.750.695.700.720.250.200; D12.776.543.750.720.700.720.500.200
Unique ID: D058476
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058476
Scope Note: A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension and NEUROPATHIC PAIN. The receptor comprises three P2X2 subunits. The P2X2 subunits also have been found associated with P2X3 RECEPTOR subunits in a heterotrimeric receptor variant.
Entry Term(s): P2X2 Purinoceptor; P2X2 Purinoceptors; P2X2 Receptor; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2
Public MeSH Note: 2011; PURINERGIC P2X2 RECEPTOR (now RECEPTORS, PURINERGIC P2X2) was indexed under RECEPTORS, PURINERGIC P2 1995-2010
History Note: 2011
Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2016/07/01

Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
        
        Receptors, Purinergic P2X1 [D12.776.157.530.400.400.750.100]
        
        Receptors, Purinergic P2X2 [D12.776.157.530.400.400.750.200]
        
        Receptors, Purinergic P2X3 [D12.776.157.530.400.400.750.300]
        
        Receptors, Purinergic P2X4 [D12.776.157.530.400.400.750.400]
        
        Receptors, Purinergic P2X5 [D12.776.157.530.400.400.750.500]
        
        Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.550.450.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.550.450.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.550.450.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.550.450.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.550.450.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.550.450.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.585.400.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.585.400.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.585.400.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.585.400.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.585.400.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Receptors, Purinergic [D12.776.543.750.695.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.695.700.720.250.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.695.700.720.250.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.695.700.720.250.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.695.700.720.250.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.695.700.720.250.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.695.700.720.250.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Purinergic [D12.776.543.750.720.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.720.700.720.500.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.720.700.720.500.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.720.700.720.500.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.720.700.720.500.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.720.700.720.500.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]

Receptors, Purinergic P2X2 Preferred

Concept UI: M0542731
Scope Note: A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension and NEUROPATHIC PAIN. The receptor comprises three P2X2 subunits. The P2X2 subunits also have been found associated with P2X3 RECEPTOR subunits in a heterotrimeric receptor variant.
Terms: Receptors, Purinergic P2X2 Preferred Term
Term UI T764256
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X2 Purinoceptors
Term UI T764257
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X2 Receptor
Term UI T764258
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2
Term UI T764259
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X2 Purinoceptor
Term UI T764262
Date01/15/2010
LexicalTag ABX
ThesaurusID NLM (2011)

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