Receptors, Purinergic P2X4 MeSH Descriptor Data 2024

MeSH Heading: Receptors, Purinergic P2X4
Tree Number(s): D12.776.157.530.400.400.750.400; D12.776.543.550.450.500.600.400; D12.776.543.585.400.500.600.400; D12.776.543.750.695.700.720.250.400; D12.776.543.750.720.700.720.500.400
Unique ID: D058848
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058848
Scope Note: A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a role in the mediation of allodynia-related NEUROPATHIC PAIN.
Entry Term(s): P2X4 Purinoceptor; P2X4 Receptor; Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4
Public MeSH Note: 2011; PURINERGIC P2X4 RECEPTOR now RECEPTORS, PURINERGIC P2X4 was indexed under RECEPTORS, PURINERGIC P2X4 1996-2010
History Note: 2011
Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2016/07/01

Entry Combination: agonists:Purinergic P2X Receptor Agonists; antagonists & inhibitors:Purinergic P2X Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
        
        Receptors, Purinergic P2X1 [D12.776.157.530.400.400.750.100]
        
        Receptors, Purinergic P2X2 [D12.776.157.530.400.400.750.200]
        
        Receptors, Purinergic P2X3 [D12.776.157.530.400.400.750.300]
        
        Receptors, Purinergic P2X4 [D12.776.157.530.400.400.750.400]
        
        Receptors, Purinergic P2X5 [D12.776.157.530.400.400.750.500]
        
        Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.550.450.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.550.450.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.550.450.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.550.450.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.550.450.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.550.450.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
        
        Receptors, Purinergic P2X1 [D12.776.543.585.400.500.600.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.585.400.500.600.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.585.400.500.600.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.585.400.500.600.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.585.400.500.600.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Receptors, Purinergic [D12.776.543.750.695.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.695.700.720.250.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.695.700.720.250.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.695.700.720.250.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.695.700.720.250.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.695.700.720.250.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.695.700.720.250.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Purinergic [D12.776.543.750.720.700]
        
        Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
        
        Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
        
        Receptors, Purinergic P2X1 [D12.776.543.750.720.700.720.500.100]
        
        Receptors, Purinergic P2X2 [D12.776.543.750.720.700.720.500.200]
        
        Receptors, Purinergic P2X3 [D12.776.543.750.720.700.720.500.300]
        
        Receptors, Purinergic P2X4 [D12.776.543.750.720.700.720.500.400]
        
        Receptors, Purinergic P2X5 [D12.776.543.750.720.700.720.500.500]
        
        Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]

Receptors, Purinergic P2X4 Preferred

Concept UI: M0544963
Scope Note: A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a role in the mediation of allodynia-related NEUROPATHIC PAIN.
Terms: Receptors, Purinergic P2X4 Preferred Term
Term UI T768230
Date03/30/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X4 Receptor
Term UI T768231
Date03/30/2010
LexicalTag ABX
ThesaurusID NLM (2011); Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4
Term UI T768232
Date03/30/2010
LexicalTag ABX
ThesaurusID NLM (2011); P2X4 Purinoceptor
Term UI T768233
Date03/30/2010
LexicalTag ABX
ThesaurusID NLM (2011)

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