MeSH Browser

MeSH Heading: Solute Carrier Family 12, Member 3
Tree Number(s): D12.776.157.530.450.625.374.500; D12.776.157.530.937.750.750; D12.776.543.585.937.875.750
Unique ID: D064486
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064486
Scope Note: Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.
Entry Term(s): NCCT Protein; Na-Cl Cotransporter; Na-Cl Symporter; Na-Cl Thiazide-Sensitive Cotransporter; SLC12A3 Cotransporter; SLC12A3 Protein; Thiazide-Sensitive Sodium-Chloride Cotransporter
Registry Numbers: 0
See Also: Gitelman Syndrome
Public MeSH Note: 2014; was indexed under CARRIER PROTEINS 1984-2001 and SODIUM CHLORIDE SYMPORTERS 2002-2013
History Note: 2014
Entry Combination: antagonists & inhibitors:Sodium Chloride Symporter Inhibitors
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2015/11/24

Entry Combination: antagonists & inhibitors:Sodium Chloride Symporter Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0581958
Registry Numbers: 0
Scope Note: Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS.
Terms: Solute Carrier Family 12, Member 3 Preferred Term
Term UI T838428
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); SLC12A3 Protein
Term UI T838432
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); SLC12A3 Cotransporter
Term UI T838433
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); NCCT Protein
Term UI T838434
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); Na-Cl Thiazide-Sensitive Cotransporter
Term UI T838435
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); Na-Cl Cotransporter
Term UI T838429
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); Thiazide-Sensitive Sodium-Chloride Cotransporter
Term UI T838431
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014); Na-Cl Symporter
Term UI T838430
Date03/11/2013
LexicalTag NON
ThesaurusID NLM (2014)

Solute Carrier Family 12, Member 3 MeSH Descriptor Data 2025