MeSH Browser

MeSH Heading: Solute Carrier Family 12, Member 2
Tree Number(s): D12.776.157.530.450.625.875.750.625; D12.776.157.530.937.750.625; D12.776.543.585.450.625.750.625; D12.776.543.585.937.875.625
Unique ID: D064506
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064506
Scope Note: Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells.
Entry Term(s): BSC2 Protein; BSC2 Transport Protein; Bumetanide-Sensitive Cotransporter 2; Bumetanide-Sensitive Sodium Potassium Chloride Cotransporter 2; NKCC1 Cotransporter; NKCC1 Protein; NKCC1 Transport Protein; SLC12A2 Cotransporter; SLC12A2 Protein; SLC12A2 Transporter; Sodium-Potassium-Chloride Cotransporter 1 Protein; Solute Carrier Family 12 (Sodium Potassium Chloride Transporters), Member 2
Registry Numbers: 0
Public MeSH Note: 2014
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2023/04/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Pumps [D12.776.157.530.450]
        
        Symporters [D12.776.157.530.450.625]
        
        Solute Carrier Family 12 [D12.776.157.530.450.625.875]
        
        Sodium-Potassium-Chloride Symporters [D12.776.157.530.450.625.875.750]
        
        Solute Carrier Family 12, Member 1 [D12.776.157.530.450.625.875.750.500]
        
        Solute Carrier Family 12, Member 2 [D12.776.157.530.450.625.875.750.625]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Solute Carrier Proteins [D12.776.157.530.937]
        
        Sodium-Potassium-Chloride Symporters [D12.776.157.530.937.750]
        
        Solute Carrier Family 12, Member 1 [D12.776.157.530.937.750.500]
        
        Solute Carrier Family 12, Member 2 [D12.776.157.530.937.750.625]
        
        Solute Carrier Family 12, Member 3 [D12.776.157.530.937.750.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Pumps [D12.776.543.585.450]
        
        Symporters [D12.776.543.585.450.625]
        
        Sodium-Potassium-Chloride Symporters [D12.776.543.585.450.625.750]
        
        Solute Carrier Family 12, Member 1 [D12.776.543.585.450.625.750.500]
        
        Solute Carrier Family 12, Member 2 [D12.776.543.585.450.625.750.625]
        
        Solute Carrier Family 12, Member 4 [D12.776.543.585.450.625.750.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Solute Carrier Proteins [D12.776.543.585.937]
        
        Sodium-Potassium-Chloride Symporters [D12.776.543.585.937.875]
        
        Solute Carrier Family 12, Member 1 [D12.776.543.585.937.875.500]
        
        Solute Carrier Family 12, Member 2 [D12.776.543.585.937.875.625]
        
        Solute Carrier Family 12, Member 3 [D12.776.543.585.937.875.750]
        
        Solute Carrier Family 12, Member 4 [D12.776.543.585.937.875.875]

Solute Carrier Family 12, Member 2 Preferred

Concept UI: M0582117
Registry Numbers: 0
Scope Note: Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells.
Terms: Solute Carrier Family 12, Member 2 Preferred Term
Term UI T838550
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); SLC12A2 Protein
Term UI T838551
Date03/13/2013
LexicalTag ABX
ThesaurusID NLM (2014); SLC12A2 Transporter
Term UI T838552
Date03/13/2013
LexicalTag ABX
ThesaurusID NLM (2014); NKCC1 Protein
Term UI T838553
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); NKCC1 Cotransporter
Term UI T838555
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); Bumetanide-Sensitive Sodium Potassium Chloride Cotransporter 2
Term UI T838556
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); Sodium-Potassium-Chloride Cotransporter 1 Protein
Term UI T838557
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); BSC2 Protein
Term UI T838558
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); BSC2 Transport Protein
Term UI T838559
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); Bumetanide-Sensitive Cotransporter 2
Term UI T838560
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); NKCC1 Transport Protein
Term UI T838561
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); SLC12A2 Cotransporter
Term UI T838562
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014); Solute Carrier Family 12 (Sodium Potassium Chloride Transporters), Member 2
Term UI T838563
Date03/13/2013
LexicalTag NON
ThesaurusID NLM (2014)

Solute Carrier Family 12, Member 2 MeSH Descriptor Data 2024