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Solute Carrier Family 12, Member 1 MeSH Descriptor Data 2024


MeSH Heading
Solute Carrier Family 12, Member 1
Tree Number(s)
D12.776.157.530.450.625.875.750.500
D12.776.157.530.937.750.500
D12.776.543.585.450.625.750.500
D12.776.543.585.937.875.500
Unique ID
D064466
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D064466
Scope Note
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.
Entry Term(s)
BSC1 Transport Protein
Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2
Kidney-Specific Na-K-Cl Symporter
NKCC2 Cotransporter
NKCC2 Protein
SLC12A1 Cotransporter
SLC12A1 Protein
Registry Number
0
See Also
Bartter Syndrome
Public MeSH Note
2014; was indexed under SYMPORTER 2001-2013
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/08
Revision Date
2023/04/05
Solute Carrier Family 12, Member 1 Preferred
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